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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AADAC All Species: 25.76
Human Site: Y151 Identified Species: 56.67
UniProt: P22760 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22760 NP_001077.2 399 45748 Y151 N Y R L A P K Y H F P I Q F E
Chimpanzee Pan troglodytes XP_516822 399 45724 Y151 N Y R L A P K Y H F P I Q F E
Rhesus Macaque Macaca mulatta XP_001106694 399 45806 Y151 N Y R L A P K Y H F P I Q F E
Dog Lupus familis XP_534309 399 45879 Y151 N Y R L A P K Y H F P N Q F E
Cat Felis silvestris
Mouse Mus musculus Q99PG0 398 45232 H150 D Y G L A P K H H F P R Q F E
Rat Rattus norvegicus Q9QZH8 398 45674 Y150 D Y G L A P K Y H F P K Q F E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505353 290 33323 F54 V Y T A V R W F L R G Q I L E
Chicken Gallus gallus XP_422836 403 44590 Y151 N Y R L A P K Y H F P V Q F E
Frog Xenopus laevis NP_001104216 403 45798 F151 D Y R L A P A F H F P T Q F D
Zebra Danio Brachydanio rerio XP_001923714 410 46788 Y154 E Y R L A P A Y H F P V Q F E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LYC1 358 40281 A122 G S F T H S S A N S A I Y D T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 92.4 75.6 N.A. 69.6 67.6 N.A. 50.8 57 54.8 48.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.2 94.9 85.7 N.A. 84.2 83.4 N.A. 60.6 77.9 71.2 66.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 73.3 80 N.A. 13.3 93.3 66.6 80 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. 20 100 86.6 86.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 39.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 82 0 19 10 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 28 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % D
% Glu: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 82 % E
% Phe: 0 0 10 0 0 0 0 19 0 82 0 0 0 82 0 % F
% Gly: 10 0 19 0 0 0 0 0 0 0 10 0 0 0 0 % G
% His: 0 0 0 0 10 0 0 10 82 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 37 10 0 0 % I
% Lys: 0 0 0 0 0 0 64 0 0 0 0 10 0 0 0 % K
% Leu: 0 0 0 82 0 0 0 0 10 0 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 46 0 0 0 0 0 0 0 10 0 0 10 0 0 0 % N
% Pro: 0 0 0 0 0 82 0 0 0 0 82 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 10 82 0 0 % Q
% Arg: 0 0 64 0 0 10 0 0 0 10 0 10 0 0 0 % R
% Ser: 0 10 0 0 0 10 10 0 0 10 0 0 0 0 0 % S
% Thr: 0 0 10 10 0 0 0 0 0 0 0 10 0 0 10 % T
% Val: 10 0 0 0 10 0 0 0 0 0 0 19 0 0 0 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 91 0 0 0 0 0 64 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _